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Turnaround by the Vikings and collapse by the Chargers make for a first in the NFL

The Minnesota Vikings and Los Angeles Chargers are the surprising last teams standing with a zero in either the win or the loss column. The Vikings beat Indianapolis 16-10 on Sunday and are now the only undefeated team remaining after losses by San Francisco and Kansas City, while the Chargers are the last winless team after Miami beat the New York Jets. That makes this season the first in the Super Bowl era, according to Sportradar, when the last undefeated team missed the playoffs the previous season and the last winless team made the previous postseason. While the Vikings and Chargers are on opposite sides of the standings, they are tied in one statistic that shows just how unlikely this 6-0 start is for Minnesota. The teams are averaging 1.5 offensive touchdowns per game for the second-lowest mark in the NFL. The Vikings scored five TDs on offense in the opener against Green Bay and…

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Why An AI Biotech Startup Launched A $600 Million Fund To Buy Stalled Drugs

Formation Bio cofounder and CEO Ben Liu has a theory about AI and drugs. Finding new ones might be the sexiest use case, but the long, grueling and expensive part of clinical development is where most drugs fail — and where AI will prove most fruitful. Liu has now raised a $600 million investment fund to prove out that thesis. “There are increasingly more good discovered drugs, and the fundamental bottleneck is how do you show they work in the clinic,” Liu tells Forbes. “What this allows us to do is to take more shots.” With the new fund, he hopes to acquire or license 10 to 15 new drugs over the next three to five years, and push them through clinical trials faster with the help of AI. That’s potentially a big advantage when every day of delay in a clinical trial can be worth millions. Investors in the new fund include research foundations, endowments, hospitals and philanthropic…

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Warm-water orcas spend past week hunting off Southern California

Three different pods of Eastern Tropical Pacific orcas were spotted off Southern California’s coastline over the weekend, from Palos Verdes down to San Diego, a species typically found further south in warmer water climates. Newport Coastal Adventures crews came upon a pod of the killer whales rarely documented off California about a mile from Laguna Beach early Saturday morning, Oct. 24, including a large male thought to be more than 60 years old called Cuitláhuac. He is commonly seen in the warmer waters of the Gulf of California. This ETP pod was spotted hunting dolphins, and though they were not documented feasting, it was clear they were after the smaller marine mammals, he said. Alisa Schulman-Janiger, co-founder of the California Killer Whale Project who has been documenting orca sightings since the late 1970s, said the same pod was spotted killing a young fin whale off San Diego…

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Gold climbs above $4,050 as Wall Street rallies ahead of Fed decision - Kitco PM Report

(Kitco NewsWire) - Spot gold and silver prices were higher in late U.S. trading Tuesday, recovering from early-session losses as declining crude oil prices eased inflation concerns and supported renewed buying interest in precious metals ahead of Wednesday's Federal Reserve monetary policy decision. Diplomatic efforts involving Iran and several regional powers helped reduce some of the immediate geopolitical risk premium in energy markets, while stronger U.S. economic data and a firmer dollar limited bullion's advance. At the latest verified afternoon price reading, spot gold was trading near $4,058.20 an ounce, up $42.00, or 1.05%, while spot silver was trading near $54.200, up $0.353, or 0.66%, on the session.Tuesday's U.S. economic reports pointed to resilient consumer demand and business investment despite elevated borrowing costs. September durable goods orders rose 1.8%, following…

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